| Agent
|
Treatment
|
| Clostridium difficile |
|
| Campylobacter jejuni |
Pediatric:
|
| Entamoeba histolytica |
|
| Giardia lamblia |
|
| Microsporidium |
|
| Cryptosporidium |
|
| Salmonella (non typhoid) |
- Treatment is not recommended routinely but should be considered if:
- Immunocompromised
- Age<6 mo or >50yo
- Has any prostheses
- Valvular heart disease
- Severe Atherosclerosis
- Active Malignancy
- Uremic
Options:
Immunocompromised patients should have 14 days of therapy
Pediatric:
- Treatment recommended if age <6 months, immunocompromised, or bacteremia
- Ceftriaxone 50-75mg/kg IV daily x 5 days (max 2g)
- TMP/SMX 8mg/kg/day (TMP) PO divided BID x 5 days
- Azithromycin 10mg/kg PO day 1, then 5mg/kg/day x 4 days
|
| Shigella |
Treatment extended for 10 days if immunocompromised'
Pediatric:
- Azithromycin 10mg/kg PO day 1 (max 500mg), then 5mg/kg/day x 4 days
- Ceftriaxone 50mg/kg IM/IV daily x 5 days (max 2g)
- TMP/SMX 8mg/kg/day (TMP) PO divided BID x 5 days (if susceptible)
|
| Vibrio Cholerae |
|
| Yersinia enterocolitica |
Antibiotics are not required unless patient is immunocompromised or systemically ill
|