Herpetic whitlow: Difference between revisions

m (Rossdonaldson1 moved page Herpetic Whitlow to Herpetic whitlow)
Line 6: Line 6:


==Clinical Features==
==Clinical Features==
[[File:Herpetic whitlow in young child.jpg|thumbnail|Herpetic whitlow]]
*Same burning, pruritic sensation as from other herpes infections
*Same burning, pruritic sensation as from other herpes infections
*Vesicular ullae
*Vesicular ullae

Revision as of 13:44, 31 October 2014

Background

  • HSV infection of distal finger[1]
    • Usually occurs from contact w/ oral herpes, or autoinoculation from genital herpes
    • Incubation period of 2-20 days, with possible prodrome of fever or malaise
    • 60% due to HSV-1, 40% due to HSV-2

Clinical Features

Herpetic whitlow
  • Same burning, pruritic sensation as from other herpes infections
  • Vesicular ullae
  • Finger may be indurated and tender (but should not be tense, as in a felon)
  • Rash develops over 7-10 days, with possible ulceration and rupture
  • Symptoms improve, crust over, and heal after 10-14 days with viral shedding terminating at this point
  • Complete resolution by 15-21 days

Diagnosis

  • If unsure of diagnosis can unroof a vesicle and send fluid for a Tzanck smear

Differential Diagnosis

Hand and finger infections

Look-Alikes

Treatment

  • Immobilization, elevation, analgesia

Anitivirals

  • Ativirals such as Acyclovir or Valacyclovir may shorten duration of infection[2]
  • Topical acyclovir 5% shortens duration and viral shedding in primary infection[2]
  • Oral acyclovir dosing - 800 mg BID initiated during prodrome may prevent recurrence

Secondary Prevention

  • Application of clean dressings to involved digits is important to prevent autoinoculation or spread to other individuals

See Also

Source

  1. Wu IB, Schwartz RA. Herpetic whitlow. Cutis. Mar 2007;79(3):193-6
  2. 2.0 2.1 Nikkels AF, Pierard GE. Treatment of mucocutaneous presentations of herpes simplex virus infections. Am J Clin Dermatol. 2002;3(7):475-87.