Polycystic kidney disease: Difference between revisions
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==Clinical Features== | ==Clinical Features== | ||
*Clinical presentation typically begins in 3rd to 4th decade of life, but may be detectable in childhood | *Clinical presentation typically begins in 3rd to 4th decade of life, but may be detectable in childhood | ||
* | *[[Abdominal pain]], [[flank pain]] and/or [[back pain]] is most common initial symptom. | ||
**enlargement of cysts | **Pain due to: | ||
**bleeding within cyst or gross hematuria with clots or perinephric hematoma | ***enlargement of cysts | ||
**urinary tract infection | ***bleeding within cyst or gross [[hematuria]] with clots or perinephric hematoma | ||
**nephrolithiasis | ***[[urinary tract infection]] | ||
*Hematuria | ***[[nephrolithiasis]] | ||
*[[Hematuria]] | |||
**self-limited | **self-limited | ||
**cysts are susceptible to traumatic injury | **cysts are susceptible to traumatic injury | ||
Revision as of 22:25, 28 September 2016
Background
- Multisystemic and progressive disorder resulting in renal cysts and renal enlargement
- Hereditary disorder, autosomal dominant
- Accounts for ~2% of new cases of renal failure each year
- Mortality
- Cardiovascular
- Infection, septicemia
- Subarachnoid hemorrhage
- Uremia
Clinical Features
- Clinical presentation typically begins in 3rd to 4th decade of life, but may be detectable in childhood
- Abdominal pain, flank pain and/or back pain is most common initial symptom.
- Pain due to:
- enlargement of cysts
- bleeding within cyst or gross hematuria with clots or perinephric hematoma
- urinary tract infection
- nephrolithiasis
- Pain due to:
- Hematuria
- self-limited
- cysts are susceptible to traumatic injury
Evaluation
- US is the imaging of choice
- CBC, BMP
- Urinalysis +/- Urine culture
References
- Torra R et al. Polycystic Kidney Disease. eMedicine. Feb 11, 2016. http://emedicine.medscape.com/article/244907-overview#showall