Template:Infectious Tenosynovitis Antibiotics: Difference between revisions
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(Fix formatting: add bullet to Animal Bites Ampicillin/Sulbactam entry) |
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''Treatment should cover [[S. aureus]], [[Streptococcus]], and [[MRSA]]'' | ''Treatment should cover [[S. aureus]], [[Streptococcus]], and [[MRSA]]'' | ||
* | *{{AntibioticDose|disease=Infectious tenosynovitis|drug=Vancomycin|dose=25-30 mg/kg IV loading dose then 15-20mg/kg IV q12hrs|context=Empiric}} PLUS | ||
* | **{{AntibioticDose|disease=Infectious tenosynovitis|drug=Levofloxacin|dose=750 mg IV once daily|context=Empiric}} (avoid in pediatrics) OR | ||
*If suspicious of [[Gonococcal]] infection then 1g IV once daily | **{{AntibioticDose|disease=Infectious tenosynovitis|drug=Ceftriaxone|dose=1g IV daily|context=Empiric}} | ||
*If suspicious of [[Gonococcal]] infection then use [[Ceftriaxone]] 1g IV once daily AND [[Chlamydia]] coverage with | |||
**{{AntibioticDose|disease=Infectious tenosynovitis|drug=Azithromycin|dose=1g PO once|context=Gonococcal}} OR | |||
**{{AntibioticDose|disease=Infectious tenosynovitis|drug=Doxycycline|dose=100mg PO twice daily|context=Gonococcal}} | |||
====Animal Bites==== | ====Animal Bites==== | ||
*{{AntibioticDose|disease=Infectious tenosynovitis|drug=Ampicillin/Sulbactam|dose=3g (50mg/kg) IV four times daily|context=Animal Bites}} | |||
====Pediatrics==== | ====Pediatrics==== | ||
* | *{{AntibioticDose|disease=Infectious tenosynovitis|drug=Ceftriaxone|dose=100mg/kg IV once daily|context=Pediatrics|population=Pediatric}} AND {{AntibioticDose|disease=Infectious tenosynovitis|drug=Metronidazole|dose=7.5mg/kg IV four times daily|context=Pediatrics|population=Pediatric}} OR | ||
* | *{{AntibioticDose|disease=Infectious tenosynovitis|drug=Clindamycin|dose=10mg/kg IV four times daily|context=Pediatrics|population=Pediatric}} AND {{AntibioticDose|disease=Infectious tenosynovitis|drug=TMP/SMX|dose=5mg/kg IV BID|context=Pediatrics|population=Pediatric}} | ||
*{{AntibioticDose|disease=Infectious tenosynovitis|drug=Ampicillin/Sulbactam|dose=50 mg/kg IV four times daily|context=Pediatrics|population=Pediatric}} | |||
====Mycobacteria related==== | |||
''Treatment should include usual therapy listed above in addition to:'' | |||
*{{AntibioticDose|disease=Infectious tenosynovitis|drug=Clarithromycin|dose=500mg PO twice daily|context=Mycobacteria}} PLUS | |||
**{{AntibioticDose|disease=Infectious tenosynovitis|drug=Ethambutol|dose=15 mg/kg PO once daily|context=Mycobacteria}} OR | |||
**{{AntibioticDose|disease=Infectious tenosynovitis|drug=Rifampin|dose=600 mg PO once daily|context=Mycobacteria}} AND consult infectious disease | |||
Latest revision as of 14:08, 20 March 2026
Treatment should cover S. aureus, Streptococcus, and MRSA
- Vancomycin 25-30 mg/kg IV loading dose then 15-20mg/kg IV q12hrs PLUS
- Levofloxacin 750 mg IV once daily (avoid in pediatrics) OR
- Ceftriaxone 1g IV daily
- If suspicious of Gonococcal infection then use Ceftriaxone 1g IV once daily AND Chlamydia coverage with
- Azithromycin 1g PO once OR
- Doxycycline 100mg PO twice daily
Animal Bites
- Ampicillin/Sulbactam 3g (50mg/kg) IV four times daily
Pediatrics
- Ceftriaxone 100mg/kg IV once daily AND Metronidazole 7.5mg/kg IV four times daily OR
- Clindamycin 10mg/kg IV four times daily AND TMP/SMX 5mg/kg IV BID
- Ampicillin/Sulbactam 50 mg/kg IV four times daily
Treatment should include usual therapy listed above in addition to:
- Clarithromycin 500mg PO twice daily PLUS
- Ethambutol 15 mg/kg PO once daily OR
- Rifampin 600 mg PO once daily AND consult infectious disease