Grey baby syndrome: Difference between revisions

Revision as of 13:28, 7 September 2016

A side effect of chloramphenicol affecting newborns of mothers who have been exposed to the drug
Thought to be related to insufficient ability of the newborn's liver to metabolize the drug, as well as insufficient renal excretion

Symptoms usually occur within 1 week of exposure and include:
- Ashen gray color of the skin
- Failure to thrive
Poor appetite
- Vomiting
- Hypotension
- Hypothermia

Authors:

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 ==Background==
-Grey baby syndrome is a side effect of chloramphenicol affecting newborns of mothers who have been exposed to the drug. Symptoms usually occur within 1 week of exposure, and include an ashen gray color of the skin (hence the name), failure to thrive, poor appetite, vomiting, hypotension, hypothermia. The cause of grey baby syndrome is thought to be related to insufficient ability of the newborn's liver to metabolize the drug, as well as insufficient renal excretion.
+*A side effect of chloramphenicol affecting newborns of mothers who have been exposed to the drug
+*Thought to be related to insufficient ability of the newborn's liver to metabolize the drug, as well as insufficient renal excretion
 ==Clinical Features==
+*Symptoms usually occur within 1 week of exposure and include:
+**Ashen gray color of the skin
+**Failure to thrive
+*Poor appetite
+**Vomiting
+**Hypotension
+**Hypothermia
 ==Differential Diagnosis==