Template:Erysipelas antibiotics: Difference between revisions
(Created page with "''Coverage for S. pyogenes'' *Penicillin G (300K U/d IM for <30 kg, 600K to 1 million U/d IM for >30 kg) OR *Amoxicillin 500mg PO q8hrs 10 days OR *[[Clindamycin]...") |
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''Coverage for [[S. pyogenes]]'' | ''Coverage for [[S. pyogenes]]'' | ||
* | *{{AntibioticDose|disease=Erysipelas|drug=Penicillin G|dose=300K U/d IM for <30 kg, 600K to 1 million U/d IM for >30 kg|context=First Line}} (first line therapy<ref name="Linke">Linke M, Booken N. Risk factors associated with a reduced response in the treatment of erysipelas. J Dtsch Dermatol Ges. 2015 Mar;13(3):217-25.</ref>) '''OR''' | ||
* | *{{AntibioticDose|disease=Erysipelas|drug=Clindamycin|dose=450mg (5mg/kg) PO q8hrs x 10 days|context=PCN Allergic}} (if PCN allergic) '''OR''' | ||
* | *{{AntibioticDose|disease=Erysipelas|drug=Cephalexin|dose=500mg (6.25mg/kg) PO q6hrs x 10 days|context=Alternative}} '''OR''' | ||
* | *{{AntibioticDose|disease=Erysipelas|drug=Ceftriaxone|dose=1g (50mg/kg) IV once daily x 10 days|context=Inpatient}} '''OR''' | ||
*[[ | *{{AntibioticDose|disease=Erysipelas|drug=Levofloxacin|dose=500mg PO/IV daily x 10 days|context=Alternative}} '''OR''' | ||
*{{AntibioticDose|disease=Erysipelas|drug=Amoxicillin/Clavulanate|dose=500mg PO BID x 10 days|context=Treatment Failure}} (generally reserved for failure of first line therapy) | |||
Bullous Erysipela or [[MRSA]] suspected: [[trimethoprim-sulfamethoxazole]], [[clindamycin]], [[doxycycline]], or [[minocycline]] | |||
====Pediatric==== | |||
*{{AntibioticDose|disease=Erysipelas|drug=Penicillin G|dose=<30kg: 300,000 U/day IM; >30kg: 600,000-1 million U/day IM|context=Pediatric First Line|population=Pediatric}} '''OR''' | |||
*{{AntibioticDose|disease=Erysipelas|drug=Cephalexin|dose=25-50mg/kg/day PO divided q6-8h x 10 days (max 500mg/dose)|context=Pediatric|population=Pediatric}} '''OR''' | |||
*{{AntibioticDose|disease=Erysipelas|drug=Clindamycin|dose=30mg/kg/day PO divided TID x 10 days (max 1.8g/day)|context=Pediatric PCN Allergy|population=Pediatric}} '''OR''' | |||
*{{AntibioticDose|disease=Erysipelas|drug=Ceftriaxone|dose=50mg/kg IV daily (max 2g) x 10 days|context=Pediatric Inpatient|population=Pediatric}} | |||
Latest revision as of 13:01, 20 March 2026
Coverage for S. pyogenes
- Penicillin G 300K U/d IM for <30 kg, 600K to 1 million U/d IM for >30 kg (first line therapy[1]) OR
- Clindamycin 450mg (5mg/kg) PO q8hrs x 10 days (if PCN allergic) OR
- Cephalexin 500mg (6.25mg/kg) PO q6hrs x 10 days OR
- Ceftriaxone 1g (50mg/kg) IV once daily x 10 days OR
- Levofloxacin 500mg PO/IV daily x 10 days OR
- Amoxicillin/Clavulanate 500mg PO BID x 10 days (generally reserved for failure of first line therapy)
Bullous Erysipela or MRSA suspected: trimethoprim-sulfamethoxazole, clindamycin, doxycycline, or minocycline
Pediatric
- Penicillin G <30kg: 300,000 U/day IM; >30kg: 600,000-1 million U/day IM OR
- Cephalexin 25-50mg/kg/day PO divided q6-8h x 10 days (max 500mg/dose) OR
- Clindamycin 30mg/kg/day PO divided TID x 10 days (max 1.8g/day) OR
- Ceftriaxone 50mg/kg IV daily (max 2g) x 10 days
- ↑ Linke M, Booken N. Risk factors associated with a reduced response in the treatment of erysipelas. J Dtsch Dermatol Ges. 2015 Mar;13(3):217-25.