Template:Animal bite antibiotics: Difference between revisions

No edit summary
(Add pediatric cat/dog bite and severe bite infection dosing)
 
(13 intermediate revisions by 6 users not shown)
Line 1: Line 1:
''Coverage for Pasteurella, Strep, and Staph''
====Cat and Dog Bites==== ''Coverage for [[Pasteurella|Pasteurella]], [[Strep|Strep]], and [[Staph|Staph]]''
====Cat and Dog Bites====
*'''Consider for high-risk wounds'''
''Coverage for Pasteurella, Strep, and Staph''
**wounds reaching the level of the muscle/tendon, wounds to the hand<ref>[[EBQ:Antibiotic prophylaxis for mammalian bites|EBQ:Antibiotic prophylaxis for mammalian bites]]</ref>, violation of bone or joint capsule, immunocompromised hosts, wounds associated with significant local edema
*Consider for high-risk wounds (see above)
*{{AntibioticDose|disease=Mammalian bites|drug=Amoxicillin/Clavulanate|dose=875mg PO BID x 5-7 days|context=Cat and dog bites|population=Adult}} OR<ref>Griego RD, Rosen T, Orengo IF, Wolf JE. Dog, cat, and human bites: a review. J Am Acad Dermatol. 1995;33:1019–29.</ref>
*[[Amoxicillin/Clavulanate|Amoxicilin-clavulanate]] 875mg PO BID x 5-7 days OR<ref>Griego RD, Rosen T, Orengo IF, Wolf JE. Dog, cat, and human bites: a review. J Am Acad Dermatol. 1995;33:1019–29.</ref>
*{{AntibioticDose|disease=Mammalian bites|drug=Doxycycline|dose=100mg PO BID x 14 days|context=Cat and dog bites penicillin allergic|population=Adult}} if penicillin allergic <ref>Talan DA, Citron DM, Abrahamian FM, Moran GJ, Goldstein EJ. Bacteriologic analysis of infected dog and cat bites. Emergency Medicine Animal Bite Infection Study Group. N Engl J Med. 1999;340:85–92.</ref>
*[[Doxycycline]] 100mg PO daily x 14 days if penicillin allergic <ref>Talan DA, Citron DM, Abrahamian FM, Moran GJ, Goldstein EJ. Bacteriologic analysis of infected dog and cat bites. Emergency Medicine Animal Bite Infection Study Group. N Engl J Med. 1999;340:85–92.</ref>
*{{AntibioticDose|disease=Mammalian bites|drug=Clindamycin|dose=450mg (5mg/kg) PO q8hrs x 7 days|context=Cat and dog bites alt|population=Adult}} PLUS
*[[Clindamycin]] 450mg (5mg/kg) PO q8hrs daily x7 days PLUS
**{{AntibioticDose|disease=Mammalian bites|drug=Ciprofloxacin|dose=500mg PO q12hrs x 7 days|context=Cat and dog bites with Clindamycin|population=Adult}} OR
**Ciprofloxacin 500mg PO q12hrs x 7 days OR
**{{AntibioticDose|disease=Mammalian bites|drug=Trimethoprim-Sulfamethoxazole DS|dose=2 DS tabs (5mg/kg) PO q12hrs|context=Cat and dog bites with Clindamycin|display=TMP/SMX|population=Adult}}
**TMP/SMX 2DS tabs (5mg/kg) PO q12hrs
 
 
====Human Bites==== All human bites should be strongly considered for antibiotic therapy.<ref>[[EBQ:Antibiotic prophylaxis for mammalian bites|EBQ:Antibiotic prophylaxis for mammalian bites]]</ref>


====Human Bites====
{{Human bite antibiotics}}
{{Human bite antibiotics}}
====Mammalian Bites Severe Infections==== *{{AntibioticDose|disease=Mammalian bites|drug=Ampicillin/Sulbactam|dose=3g IV (50mg/kg) q6hrs|context=Severe mammalian bite infection|population=Adult}} OR
*{{AntibioticDose|disease=Mammalian bites|drug=Cefoxitin|dose=1g IV q8hrs (25mg/kg q6hrs)|context=Severe mammalian bite infection|population=Adult}} OR
*{{AntibioticDose|disease=Mammalian bites|drug=Piperacillin/Tazobactam|dose=4.5g IV (80mg/kg) q8hrs|context=Severe mammalian bite infection|population=Adult}} OR
*{{AntibioticDose|disease=Mammalian bites|drug=Ceftriaxone|dose=1g (50mg/kg) IV once|context=Severe mammalian bite infection|population=Adult}} + {{AntibioticDose|disease=Mammalian bites|drug=Metronidazole|dose=500mg IV q8hrs|context=Severe mammalian bite infection with Ceftriaxone|population=Adult}} OR
*{{AntibioticDose|disease=Mammalian bites|drug=Clindamycin|dose=600mg IV q8hrs|context=Severe mammalian bite infection alt|population=Adult}} PLUS
**{{AntibioticDose|disease=Mammalian bites|drug=Trimethoprim-Sulfamethoxazole DS|dose=5mg/kg IV q12hrs|context=Severe mammalian bite with Clindamycin|display=TMP/SMX|population=Adult}} OR
**{{AntibioticDose|disease=Mammalian bites|drug=Ciprofloxacin|dose=400mg IV q12hrs|context=Severe mammalian bite with Clindamycin|population=Adult}} OR
====Pediatric Cat and Dog Bites====
*{{AntibioticDose|disease=Mammalian bites|drug=Amoxicillin/Clavulanate|dose=25-45mg/kg/day PO divided BID x 5-7 days|context=Pediatric cat and dog bites|population=Pediatric}} '''OR'''
*{{AntibioticDose|disease=Mammalian bites|drug=Clindamycin|dose=30mg/kg/day PO divided TID (max 1.8g/day)|context=Pediatric PCN allergy|population=Pediatric}} + {{AntibioticDose|disease=Mammalian bites|drug=Trimethoprim-Sulfamethoxazole DS|display=TMP/SMX|dose=8-12mg/kg/day (TMP) PO divided BID|context=Pediatric PCN allergy with Clindamycin|population=Pediatric}}


====Mammalian Bites Severe Infections====
====Pediatric Severe Bite Infections====
*[[Ampicillin/Sulbactam]] 3g IV (50mg/kg IV) q 6hrs daily OR
*{{AntibioticDose|disease=Mammalian bites|drug=Ampicillin/Sulbactam|dose=50mg/kg IV q6hrs (max 3g/dose)|context=Pediatric Severe|population=Pediatric}} '''OR'''
*[[Cefoxitin]] 1g IV q8hrs (25mg/kg q6hrs) OR
*{{AntibioticDose|disease=Mammalian bites|drug=Piperacillin/Tazobactam|dose=80mg/kg IV q8hrs (max 4.5g)|context=Pediatric Severe|population=Pediatric}} '''OR'''
*[[Pipericillin/Tazobactam]] 4.5g IV (80mg/kg IV) q8hrs OR
*{{AntibioticDose|disease=Mammalian bites|drug=Ceftriaxone|dose=50mg/kg IV daily (max 2g)|context=Pediatric Severe|population=Pediatric}} + {{AntibioticDose|disease=Mammalian bites|drug=Metronidazole|dose=7.5mg/kg IV q8hrs (max 500mg)|context=Pediatric Severe with Ceftriaxone|population=Pediatric}}
*[[Ceftriaxone]] 1g (50mg/kg IV) once + [[Metronidazole]] 500mg IV q8hrs OR
*[[Clindamycin]] 600mg IV q8hrs PLUS
**[[TMP/SMX]] 5mg/kg IV q12hrs OR
**[[Ciprofloxacin]] 400mg IV q12hrs OR

Latest revision as of 12:59, 20 March 2026

====Cat and Dog Bites==== Coverage for Pasteurella, Strep, and Staph

  • Consider for high-risk wounds
    • wounds reaching the level of the muscle/tendon, wounds to the hand[1], violation of bone or joint capsule, immunocompromised hosts, wounds associated with significant local edema
  • Amoxicillin/Clavulanate 875mg PO BID x 5-7 days OR[2]
  • Doxycycline 100mg PO BID x 14 days if penicillin allergic [3]
  • Clindamycin 450mg (5mg/kg) PO q8hrs x 7 days PLUS


====Human Bites==== All human bites should be strongly considered for antibiotic therapy.[4]

Requires polymicrobial coverage for: S. aureus, Strep Viridans, Bacteroides, Coagulase-neg Staph, Eikenella, Fusobacterium, Cornebacterium, peptostreptococus

Pediatric:

====Mammalian Bites Severe Infections==== *Ampicillin/Sulbactam 3g IV (50mg/kg) q6hrs OR

Pediatric Cat and Dog Bites

Pediatric Severe Bite Infections

  1. ↑ EBQ:Antibiotic prophylaxis for mammalian bites
  2. ↑ Griego RD, Rosen T, Orengo IF, Wolf JE. Dog, cat, and human bites: a review. J Am Acad Dermatol. 1995;33:1019–29.
  3. ↑ Talan DA, Citron DM, Abrahamian FM, Moran GJ, Goldstein EJ. Bacteriologic analysis of infected dog and cat bites. Emergency Medicine Animal Bite Infection Study Group. N Engl J Med. 1999;340:85–92.
  4. ↑ EBQ:Antibiotic prophylaxis for mammalian bites
Retrieved from "https://www.wikem.org/w/index.php?title=Template:Animal_bite_antibiotics&oldid=386803"