Polycystic kidney disease: Difference between revisions
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==Clinical Features== | ==Clinical Features== | ||
*Clinical presentation typically begins in 3rd to 4th decade of life, but may be detectable in childhood | *Clinical presentation typically begins in 3rd to 4th decade of life, but may be detectable in childhood | ||
*Pain in abdomen/flank/back is most common initial symptom | *Pain in abdomen/flank/back is most common initial symptom. Pain can be due to: | ||
**enlargement of cysts | |||
**bleeding within cyst or gross hematuria with clots or perinephric hematoma | |||
**urinary tract infection | |||
**nephrolithiasis | |||
*Hematuria | |||
**self-limited | |||
**cysts are susceptible to traumatic injury | |||
==Evaluation== | ==Evaluation== | ||
Revision as of 18:22, 28 September 2016
Background
- Multisystemic and progressive disorder resulting in renal cysts and renal enlargement
- Hereditary disorder, autosomal dominant
- Accounts for ~2% of new cases of renal failure each year
- Mortality
- Cardiovascular
- Infection, septicemia
- Subarachnoid hemorrhage
- Uremia
Clinical Features
- Clinical presentation typically begins in 3rd to 4th decade of life, but may be detectable in childhood
- Pain in abdomen/flank/back is most common initial symptom. Pain can be due to:
- enlargement of cysts
- bleeding within cyst or gross hematuria with clots or perinephric hematoma
- urinary tract infection
- nephrolithiasis
- Hematuria
- self-limited
- cysts are susceptible to traumatic injury
Evaluation
- US
- BMP
References
- Torra R et al. Polycystic Kidney Disease. eMedicine. Feb 11, 2016. http://emedicine.medscape.com/article/244907-overview#showall