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Fibrinogen - Revision history
2026-04-17T19:10:24Z
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Danbot: Create lab page for Fibrinogen with EM-focused content and references
2026-03-22T06:58:13Z
<p>Create lab page for Fibrinogen with EM-focused content and references</p>
<p><b>New page</b></p><div>==Background==<br />
*Glycoprotein (Factor I) produced by the liver; precursor to fibrin in the coagulation cascade<br />
*Acute-phase reactant<br />
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==Normal Values==<br />
*Normal: 200-400 mg/dL<br />
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==Interpretation==<br />
*Low fibrinogen (<200 mg/dL): DIC, massive hemorrhage, liver failure, thrombolytic therapy, dilution from massive transfusion<br />
**Critical level: <100 mg/dL requires replacement with cryoprecipitate (goal >150-200 mg/dL in active bleeding)<br />
*Elevated fibrinogen: acute-phase reactant (infection, inflammation, malignancy, pregnancy)<br />
*Important to monitor in DIC, massive transfusion, and postpartum hemorrhage<br />
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==See Also==<br />
*[[DIC]]<br />
*[[Coagulation Studies]]<br />
*[[Massive transfusion]]<br />
*[[Cryoprecipitate]]<br />
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==References==<br />
<references/><br />
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[[Category:Labs]]</div>
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