Ihearttroponin: /* See Also */

2020-03-24T12:44:41Z

Ihearttroponin at 12:44, 24 March 2020

2020-03-24T12:44:14Z

← Older revision		Revision as of 12:44, 24 March 2020
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	==Administration==		==Administration==
	*Type:		*Type: [[Neuromuscular blocker]]
	*Dosage Forms:		*Dosage Forms: Injection
	*Routes of Administration:		*Routes of Administration: IV
	*Common Trade Names:		*Common Trade Names: Nimbex

	==Adult Dosing==		==Adult Dosing==
			*Induction
			**150-200 mcg/kg IV x 1
			*Maintenance
			**Intermittent
			***30 mcg/kg IV q20 min PRN (Start ~50 min after induction dose)
			**Continuous
			***1-2 mcg/kg/min IV (though rates may vary widely)

	==Pediatric Dosing==		==Pediatric Dosing==
			*Induction
			**1-23 months: 150 mcg/kg IVx1
			**2-12 years old: 100-150 mcg/kg IV x1
			**>12 years old: 150-200 mcg/kg IV x1
			*Maintenance
			**>2 years old: 1-2 mcg/kg min (though rates may vary widely)

	==Special Populations==		==Special Populations==
	===[[Drug pregnancy categories\|Pregnancy Rating]]===		===[[Drug pregnancy categories\|Pregnancy Rating]]===
	*		* Caution advised, insufficient data

	===Lactation risk===		===Lactation risk===
	*		*Caution advised, insufficient data

	===Renal Dosing===		===Renal Dosing===
	*Adult:		*Adult: Not defined, consider extended interval between dose administration and intubation if [[ESRD]]
	*Pediatric:		*Pediatric: Not defined, consider extended interval between dose administration and intubation if [[ESRD]]

	===Hepatic Dosing===		===Hepatic Dosing===
	*Adult:		*Adult: Not defined, onset 1 minute faster than healthy controls
	*Pediatric:		*Pediatric: Not defined, onset 1 minute faster than healthy controls

	==Contraindications==		==Contraindications==
	*Allergy to class/drug		*Allergy to class/drug
			*Neonates (benzyl alcohol-containing forms)
			*Caution if neuromuscular disease, burns, asthma, electrolyte abnormalities

	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
			*Hypersensitivity reaction
			*[[Anaphylaxis]]/[[Anaphylactoid reaction]]
			*Bronchospasm
			*Hypotension
			*Respiratory depression
			*Prolonged paralysis

	===Common===		===Common===
			*Bradycardia
			*Hypotension
			*Flushing
			*Bronchospasm
			*Rash

	==Pharmacology==		==Pharmacology==
	*Half-life:		*Half-life: 22-29 minutes
	*Metabolism:		*Metabolism: Liver
	*Excretion:		*Excretion: Urine

	==Mechanism of Action==		==Mechanism of Action==
			*Binds to motor end-plate cholinergic receptor, antagonizing acetylcholine activity and producing neuromuscular blockade

	==Comments==		==Comments==
			Cisatricurium can also be used as adjunct therapy for [[ARDS]]. Clinical practice guidelines recommend a short course for patients with early
			sepsis-related ARDS with a PaO2/FiO2 less than 150 mmHg.<ref>Papazian L, Forel JM, Gacouin A, et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363(12):1107–1116. doi:10.1056/NEJMoa1005372</ref>

	==See Also==		==See Also==
			*Neuromuscular blocker

	==References==		==References==

Rossdonaldson1: Created page with "==Administration== Type: Dosage Forms: Routes of Administration: Common Trade Names: ==Adult Dosing== ==Pediatric Dosing== ==Special Populations== ===Drug pregnan..."

2020-03-23T22:30:37Z

Created page with "==Administration== *Type: *Dosage Forms: *Routes of Administration: *Common Trade Names: ==Adult Dosing== ==Pediatric Dosing== ==Special Populations== ===Drug pregnan..."

New page

==Administration==
*Type:
*Dosage Forms:
*Routes of Administration:
*Common Trade Names:

==Adult Dosing==

==Pediatric Dosing==

==Special Populations==
===[[Drug pregnancy categories|Pregnancy Rating]]===
*

===Lactation risk===
*

===Renal Dosing===
*Adult:
*Pediatric:

===Hepatic Dosing===
*Adult:
*Pediatric:

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
===Serious===

===Common===

==Pharmacology==
*Half-life:
*Metabolism:
*Excretion:

==Mechanism of Action==

==Comments==

==See Also==

==References==
<references/>

[[Category:Pharmacology]]

← Older revision		Revision as of 12:44, 24 March 2020
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	==See Also==		==See Also==
	*Neuromuscular blocker		*[[Neuromuscular blocker]]

	==References==		==References==

Cisatricurium - Revision history

Ihearttroponin: /* See Also */

Ihearttroponin at 12:44, 24 March 2020

Rossdonaldson1: Created page with "==Administration== *Type: *Dosage Forms: *Routes of Administration: *Common Trade Names: ==Adult Dosing== ==Pediatric Dosing== ==Special Populations== ===Drug pregnan..."

Rossdonaldson1: Created page with "==Administration== Type: Dosage Forms: Routes of Administration: Common Trade Names: ==Adult Dosing== ==Pediatric Dosing== ==Special Populations== ===Drug pregnan..."