https://wikem.org/w/index.php?action=history&feed=atom&title=Bisacodyl%2Fen 2026-04-17T18:07:51Z Revision history for this page on the wiki MediaWiki 1.38.2 https://wikem.org/w/index.php?title=Bisacodyl/en&diff=380322&oldid=prev 2026-01-06T21:40:45Z

<p>Updating to match new version of source page</p> <p><b>New page</b></p><div>&lt;languages/&gt;<br /> <br /> ==Administration==<br /> <br /> *Type: [[Special:MyLanguage/laxative|laxative]]<br /> *Dosage Forms: tablet, enema, suppository<br /> *Dosage Strengths: tablet: 5mg; enema: 10mg/30mL; suppository: 10mg<br /> *Routes of Administration: PO, PR<br /> *Common Trade Names: Dulcolax, Correctol, BisacEvac, Bisacolax, Codulax, Alophen, Feen A Mint, Fleet Stimulant Laxative, Laxit, Modane<br /> <br /> <br /> ==Adult Dosing==<br /> <br /> *5-30mg PO daily<br /> *10mg suppository daily<br /> <br /> <br /> ==Pediatric Dosing==<br /> <br /> *6-11 yrs: 5mg or rectally daily<br /> <br /> ==Special Populations==<br /> <br /> *[[Special:MyLanguage/Drug Ratings in Pregnancy|Pregnancy Rating]]: A<br /> *[[Special:MyLanguage/Lactation risk categories|Lactation risk]]: infant risk cannot be ruled out<br /> <br /> ===Renal Dosing===<br /> <br /> *Adult:<br /> *Pediatric:<br /> <br /> ===Hepatic Dosing===<br /> <br /> *Adult:<br /> *Pediatric:<br /> <br /> <br /> ==Contraindications==<br /> <br /> *Allergy to class/drug<br /> *Appendicitis<br /> *Bowel obstruction<br /> *Gastroenteritis<br /> <br /> ==Adverse Reactions==<br /> <br /> <br /> ===Serious===<br /> <br /> *Colonic atony<br /> <br /> ===Common===<br /> <br /> *Abdominal discomfort/colic, diarrhea, proctitis (with suppository use)<br /> <br /> ==Pharmacology==<br /> <br /> *Half-life: 8 hr<br /> *Metabolism: Metabolized to BHPM in the colon<br /> *Excretion: Urine and bile<br /> <br /> <br /> ==Mechanism of Action==<br /> <br /> *Stimulates peristalsis via parasympathetic reflexes<br /> <br /> ==Comments==<br /> <br /> <br /> ==See Also==<br /> <br /> *[[Special:MyLanguage/Constipation|Constipation]]<br /> <br /> ==References==<br /> <br /> *Ahlfors CE. Benzyl alcohol, kernicterus, and unbound bilirubin. J Pediatr. 2001;139(2):317-319. [PubMed 11487763]<br /> *Centers for Disease Control (CDC). Neonatal deaths associated with use of benzyl alcohol—United States. MMWR Morb Mortal Wkly Rep. 1982;31(22):290-291. http://www.cdc.gov/mmwr/preview/mmwrhtml/00001109.htm [PubMed 6810084]<br /> *Christie J, Rose S. Constipation, diarrhea, hemorrhoids, and fecal incontinence. In: Pregnancy in gastrointestinal disorders. Bethesda (MD): ACG Monograph American College of Physicians; 2007. p. 4–9. Available at https://www.acg.gi.org<br /> *Ducodyl (bisacodyl) [prescribing information]. Troy, MI: Prime Marketing; received January 2019.<br /> *Friedrich C, Richter E, Trommeshauser D, et al, &quot;Absence of Excretion of the Active Moiety of Bisacodyl and Sodium Picosulfate Into Human Breast Milk: An Open-Label, Parallel-Group, Multiple-Dose Study in Healthy Lactating Women,&quot; Drug Metab Pharmacokinet, 2011, 26(5):458-64. [PubMed 21697613]<br /> *&quot;Inactive&quot; ingredients in pharmaceutical products: update (subject review). Pediatrics.1997;99(2):268-278. [PubMed 9024461]<br /> *Tabbers MM, DiLorenzo C, Berger MY, et al. Evaluation and treatment of functional constipation in infants and children: evidence-based recommendations from ESPGHAN and NASPGHAN. J Pediatr Gastroenterol Nutr. 2014;58(2):258-274. [PubMed 24345831]<br /> <br /> &lt;references/&gt;<br /> [[Category:Pharmacology]] [[Category:GI]]</div>

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