Aplastic crisis - Revision history

ClaireLewis at 23:40, 30 September 2019

2019-09-30T23:40:28Z

← Older revision		Revision as of 23:40, 30 September 2019
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	*[[Sickle cell crisis]]		*[[Sickle cell crisis]]
	*[[Anemia]]		*[[Anemia]]
	*Increased fatigue, pallor		*Increased [[fatigue]], pallor
	*Activity intolerance		*Activity intolerance
	*Shortness of breath		*[[Shortness of breath]]

	==Causes==		==Causes==
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	==Labs==		==Labs==
	*CBC with retic count		*CBC with retic count
	**Decrease from baseline hemoglobin/hematocrit		**[[anemia\|Decrease from baseline hemoglobin/hematocrit]]
	**Precipitous drop in reticulocyte count (or lack of response)		**Precipitous drop in reticulocyte count (or lack of response)

	==Management==		==Management==
	*~~Admit~~		*[[pRBCs\|Transfusion]] using extended antigen-typed, leuko-depleted pRBCs
	*Transfusion using extended antigen-typed, leuko-depleted pRBCs
	*Droplet precautions		*Droplet precautions

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	*Typically in 1-2 weeks		*Typically in 1-2 weeks
	*Often marked by hyperbilirubinemia, and called a “hyperhemolytic” phase<ref>http://www.ihtc.org/medical-professionals/blood-disorders/sickle-cell-disease/aplastic-crisis-intervention/</ref>		*Often marked by hyperbilirubinemia, and called a “hyperhemolytic” phase<ref>http://www.ihtc.org/medical-professionals/blood-disorders/sickle-cell-disease/aplastic-crisis-intervention/</ref>

			==Disposition==
			*Admit

	==Also See==		==Also See==

ClaireLewis: /* Causes */

2019-08-15T17:22:39Z

Causes

← Older revision		Revision as of 17:22, 15 August 2019
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	*[[Erythema Infectiosum (Fifth disease)]]		*[[Erythema Infectiosum (Fifth disease)]]
	**Invades and destroys red blood cell precursors and halts the red cell production		**Invades and destroys red blood cell precursors and halts the red cell production
	*EBV		*[[EBV]]
	*Strep infection		*[[Strep]] infection
	*Use of hydroxyurea		*Use of [[hydroxyurea]]

	==Labs==		==Labs==

Adamhaag at 18:34, 19 August 2017

2017-08-19T18:34:05Z

← Older revision		Revision as of 18:34, 19 August 2017
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	*Admit		*Admit
	*Transfusion using extended antigen-typed, leuko-depleted pRBCs		*Transfusion using extended antigen-typed, leuko-depleted pRBCs
			*Droplet precautions

	==Recovery Phase==		==Recovery Phase==

Rossdonaldson1: Text replacement - "H/H" to "hemoglobin/hematocrit"

2016-08-31T16:23:22Z

Text replacement - "H/H" to "hemoglobin/hematocrit"

← Older revision		Revision as of 16:23, 31 August 2016
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	==Labs==		==Labs==
	*CBC with retic count		*CBC with retic count
	**Decrease from baseline H/H		**Decrease from baseline hemoglobin/hematocrit
	**Precipitous drop in reticulocyte count (or lack of response)		**Precipitous drop in reticulocyte count (or lack of response)

Neil.m.young: Text replacement - " w/ " to " with "

2016-07-13T17:21:12Z

Text replacement - " w/ " to " with "

← Older revision		Revision as of 17:21, 13 July 2016
Line 18:		Line 18:

	==Labs==		==Labs==
	*CBC w/ retic count		*CBC with retic count
	**Decrease from baseline H/H		**Decrease from baseline H/H
	**Precipitous drop in reticulocyte count (or lack of response)		**Precipitous drop in reticulocyte count (or lack of response)

Rossdonaldson1: Text replacement - "==Clinical Presentation==" to "==Clinical Features=="

2016-07-12T16:28:20Z

Text replacement - "==Clinical Presentation==" to "==Clinical Features=="

← Older revision		Revision as of 16:28, 12 July 2016
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	*Clinically common in [[Sickle cell crisis]] and [[Hereditary Spherocytosis (HS)]]		*Clinically common in [[Sickle cell crisis]] and [[Hereditary Spherocytosis (HS)]]

	==Clinical ~~Presentation~~==		==Clinical Features==
	*[[Sickle cell crisis]]		*[[Sickle cell crisis]]
	*[[Anemia]]		*[[Anemia]]

Neil.m.young: Text replacement - "==Source==" to "==References== "

2016-06-27T12:54:40Z

Text replacement - "==Source==" to "==References== <references/>"

← Older revision		Revision as of 12:54, 27 June 2016
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	*[[Sickle cell crisis]]		*[[Sickle cell crisis]]

	==~~Source~~==		==References==
			<references/>
	*Janz TJ, Hamilton GC: Anemia, Polycythemia, and White Blood Cell Disorders, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 7. St. Louis, Mosby, Inc., 2010, (Ch) 119:p 1568-1574.		*Janz TJ, Hamilton GC: Anemia, Polycythemia, and White Blood Cell Disorders, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 7. St. Louis, Mosby, Inc., 2010, (Ch) 119:p 1568-1574.
	*http://www.ihtc.org/medical-professionals/blood-disorders/sickle-cell-disease/aplastic-crisis-intervention/ - last accessed 1/6/15		*http://www.ihtc.org/medical-professionals/blood-disorders/sickle-cell-disease/aplastic-crisis-intervention/ - last accessed 1/6/15

Neil.m.young: Neil.m.young moved page Aplastic Crisis to Aplastic crisis

2015-03-15T18:31:49Z

Neil.m.young moved page Aplastic Crisis to Aplastic crisis

← Older revision	Revision as of 18:31, 15 March 2015
(No difference)

Arsmd: new page, new sections, hyperlinks, citations

2015-01-07T15:26:30Z

new page, new sections, hyperlinks, citations

New page

==Background==
*Also called Reticulocytopenia: abnormal decrease of reticulocytes in the body
*Clinically common in [[Sickle cell crisis]] and [[Hereditary Spherocytosis (HS)]]

==Clinical Presentation==
*[[Sickle cell crisis]]
*[[Anemia]]
*Increased fatigue, pallor
*Activity intolerance
*Shortness of breath

==Causes==
*[[Erythema Infectiosum (Fifth disease)]]
**Invades and destroys red blood cell precursors and halts the red cell production
*EBV
*Strep infection
*Use of hydroxyurea

==Labs==
*CBC w/ retic count
**Decrease from baseline H/H
**Precipitous drop in reticulocyte count (or lack of response)

==Management==
*Admit
*Transfusion using extended antigen-typed, leuko-depleted pRBCs

==Recovery Phase==
*Typically in 1-2 weeks
*Often marked by hyperbilirubinemia, and called a “hyperhemolytic” phase<ref>http://www.ihtc.org/medical-professionals/blood-disorders/sickle-cell-disease/aplastic-crisis-intervention/</ref>

==Also See==
*[[Erythema Infectiosum (Fifth disease)]]
*[[Hereditary Spherocytosis (HS)]]
*[[Sickle cell crisis]]

==Source==
*Janz TJ, Hamilton GC: Anemia, Polycythemia, and White Blood Cell Disorders, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 7. St. Louis, Mosby, Inc., 2010, (Ch) 119:p 1568-1574.
*http://www.ihtc.org/medical-professionals/blood-disorders/sickle-cell-disease/aplastic-crisis-intervention/ - last accessed 1/6/15

[[Category:ID]]
[[Category:Heme/Onc]]