Acute hepatic failure - Revision history

Danbot: Move calculators to own section with header (visible in TOC), expanded, before External Links

2026-03-21T15:08:08Z

Move calculators to own section with header (visible in TOC), expanded, before External Links

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 *Admission to ICU with early consideration for transportation to transplant center
 ==See Also== <!--T:23-->
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 [[Category:GI]]
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Danbot: Add Child-Pugh Score calculator (collapsible)

2026-03-21T13:51:22Z

Add Child-Pugh Score calculator (collapsible)

← Older revision		Revision as of 13:51, 21 March 2026
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	<div class="mw-collapsible-content">		<div class="mw-collapsible-content">
	{{MELD_Calculator}}		{{MELD_Calculator}}
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			</div>

			<div class="mw-collapsible mw-collapsed" style="border:1px solid #aaa; padding:5px; margin-top:10px;">
			<div style="font-weight:bold;">📊 Child-Pugh Score Calculator [show]</div>
			<div class="mw-collapsible-content">
			{{Child_Pugh_Calculator}}
	</div>		</div>
	</div>		</div>

Danbot: Add MELD Score calculator (collapsible)

2026-03-21T13:51:17Z

Add MELD Score calculator (collapsible)

← Older revision		Revision as of 13:51, 21 March 2026
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	[[Category:GI]]		[[Category:GI]]
	</translate>		</translate>

			<div class="mw-collapsible mw-collapsed" style="border:1px solid #aaa; padding:5px; margin-top:10px;">
			<div style="font-weight:bold;">📊 MELD Score Calculator [show]</div>
			<div class="mw-collapsible-content">
			{{MELD_Calculator}}
			</div>
			</div>

Ostermayer: Marked this version for translation

2026-01-06T17:02:15Z

Marked this version for translation

← Older revision		Revision as of 17:02, 6 January 2026
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	==Background==		==Background== <!--T:1-->

			<!--T:2-->
	[[File:Liver vascular anatomy.png\|thumb\|Liver vascular anatomy.]]		[[File:Liver vascular anatomy.png\|thumb\|Liver vascular anatomy.]]

	===Definitions===		===Definitions=== <!--T:3-->

			<!--T:4-->
	*Hyperacute liver failure: encephalopathy occurs within 7 days of the onset of jaundice; this subset is likely to survive with medical management despite the high incidence of cerebral edema<ref>O’Grady, JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet. July 1993, Volume 342, Issue 8866, Page 273-275</ref>		*Hyperacute liver failure: encephalopathy occurs within 7 days of the onset of jaundice; this subset is likely to survive with medical management despite the high incidence of cerebral edema<ref>O’Grady, JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet. July 1993, Volume 342, Issue 8866, Page 273-275</ref>
	*Acute liver failure: interval of 8-28 days from jaundice to encephalopathy; this subset has a high incidence of cerebral edema and a poorer prognosis without liver transplant<ref>O’Grady, JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet. July 1993, Volume 342, Issue 8866, Page 273-275</ref>		*Acute liver failure: interval of 8-28 days from jaundice to encephalopathy; this subset has a high incidence of cerebral edema and a poorer prognosis without liver transplant<ref>O’Grady, JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet. July 1993, Volume 342, Issue 8866, Page 273-275</ref>
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	===Other Rare Causes of Acute Liver Failure===		===Other Rare Causes of Acute Liver Failure=== <!--T:5-->

			<!--T:6-->
	*'''[[Special:MyLanguage/Wilson's disease\|Wilson's disease]]''': unexplained elevations in LFTs, neuro-psychiatric symptoms, Kayser-Fleischer rings on eye exam		*'''[[Special:MyLanguage/Wilson's disease\|Wilson's disease]]''': unexplained elevations in LFTs, neuro-psychiatric symptoms, Kayser-Fleischer rings on eye exam
	*'''[[Special:MyLanguage/Autoimmune hepatitis\|Autoimmune hepatitis]]''': more common in women, liver disease without explanation, may have family history of other autoimmune disorders		*'''[[Special:MyLanguage/Autoimmune hepatitis\|Autoimmune hepatitis]]''': more common in women, liver disease without explanation, may have family history of other autoimmune disorders
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	==Clinical Features==		==Clinical Features== <!--T:7-->

			<!--T:8-->
	[[File:Jaundice08.jpg\|thumb\|Jaundice of the skin]]		[[File:Jaundice08.jpg\|thumb\|Jaundice of the skin]]
	[[File:SpiderAngioma.jpg\|thumb\|Spider angioma]]		[[File:SpiderAngioma.jpg\|thumb\|Spider angioma]]
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	==Differential Diagnosis==		==Differential Diagnosis== <!--T:9-->


	===[[Special:MyLanguage/Encephalopathy\|Encephalopathy]] (altered mental status)===		===[[Special:MyLanguage/Encephalopathy\|Encephalopathy]] (altered mental status)=== <!--T:10-->

			<!--T:11-->
	*[[Special:MyLanguage/Hypoglycemia\|Hypoglycemia]]		*[[Special:MyLanguage/Hypoglycemia\|Hypoglycemia]]
	*[[Special:MyLanguage/Hypoxia\|Hypoxia]]		*[[Special:MyLanguage/Hypoxia\|Hypoxia]]
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	===[[Special:MyLanguage/Jaundice\|Jaundice]]===		===[[Special:MyLanguage/Jaundice\|Jaundice]]=== <!--T:12-->

			<!--T:13-->
	*[[Special:MyLanguage/Hepatic dysfunction\|Hepatic dysfunction]]		*[[Special:MyLanguage/Hepatic dysfunction\|Hepatic dysfunction]]
	*[[Special:MyLanguage/Biliary disease\|Biliary disease]] (e.g. [[Special:MyLanguage/Choledocholithiasis\|CBD obstruction]])		*[[Special:MyLanguage/Biliary disease\|Biliary disease]] (e.g. [[Special:MyLanguage/Choledocholithiasis\|CBD obstruction]])
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	==Evaluation==		==Evaluation== <!--T:14-->


	===Labs===		===Labs=== <!--T:15-->

			<!--T:16-->
	*[[Special:MyLanguage/LFTs\|LFTs]]		*[[Special:MyLanguage/LFTs\|LFTs]]
	**AST and ALT		**AST and ALT
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	===Imaging===		===Imaging=== <!--T:17-->

			<!--T:18-->
	*Consider [[Special:MyLanguage/RUQ US\|RUQ US]] or CT in patients with jaundice to evaluate for a mechanical obstruction		*Consider [[Special:MyLanguage/RUQ US\|RUQ US]] or CT in patients with jaundice to evaluate for a mechanical obstruction
	*Otherwise, tailor imaging towards specific complaints		*Otherwise, tailor imaging towards specific complaints
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	==Management==		==Management== <!--T:19-->

			<!--T:20-->
	*Treatment is mostly supportive and tailored towards the specific etiology		*Treatment is mostly supportive and tailored towards the specific etiology
	*Early consideration regarding transporting patient to a transplant center given potential for rapid deterioration		*Early consideration regarding transporting patient to a transplant center given potential for rapid deterioration
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	==Disposition==		==Disposition== <!--T:21-->

			<!--T:22-->
	*Admission to ICU with early consideration for transportation to transplant center		*Admission to ICU with early consideration for transportation to transplant center


	==See Also==		==See Also== <!--T:23-->

			<!--T:24-->
	*[[Special:MyLanguage/Jaundice\|Jaundice]]		*[[Special:MyLanguage/Jaundice\|Jaundice]]
	*[[Special:MyLanguage/Cirrhosis\|Cirrhosis]]		*[[Special:MyLanguage/Cirrhosis\|Cirrhosis]]
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	==References==		==References== <!--T:25-->

			<!--T:26-->
	<references/>		<references/>

			<!--T:27-->
	[[Category:GI]]		[[Category:GI]]
	</translate>		</translate>

Ostermayer: Prepared the page for translation

2026-01-04T21:36:23Z

Prepared the page for translation

Show changes

Rossdonaldson1 at 23:03, 13 November 2024

2024-11-13T23:03:34Z

← Older revision		Revision as of 23:03, 13 November 2024
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	==Background==		==Background==
	[[File:~~Sobo 1906 389~~.png\|thumb\|~~Inferior view of the liver with surface showing lobes and impressions~~.]]		[[File:Liver vascular anatomy.png\|thumb\|Liver vascular anatomy.]]
	===Definitions===		===Definitions===
	*Hyperacute liver failure: encephalopathy occurs within 7 days of the onset of jaundice; this subset is likely to survive with medical management despite the high incidence of cerebral edema<ref>O’Grady, JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet. July 1993, Volume 342, Issue 8866, Page 273-275</ref>		*Hyperacute liver failure: encephalopathy occurs within 7 days of the onset of jaundice; this subset is likely to survive with medical management despite the high incidence of cerebral edema<ref>O’Grady, JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet. July 1993, Volume 342, Issue 8866, Page 273-275</ref>

Rossdonaldson1: /* Background */

2024-11-13T22:58:47Z

Background

← Older revision		Revision as of 22:58, 13 November 2024
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	==Background==		==Background==
			[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]
	===Definitions===		===Definitions===
	*Hyperacute liver failure: encephalopathy occurs within 7 days of the onset of jaundice; this subset is likely to survive with medical management despite the high incidence of cerebral edema<ref>O’Grady, JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet. July 1993, Volume 342, Issue 8866, Page 273-275</ref>		*Hyperacute liver failure: encephalopathy occurs within 7 days of the onset of jaundice; this subset is likely to survive with medical management despite the high incidence of cerebral edema<ref>O’Grady, JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet. July 1993, Volume 342, Issue 8866, Page 273-275</ref>

Rossdonaldson1: /* Differential Diagnosis */

2022-09-07T21:25:23Z

Differential Diagnosis

← Older revision		Revision as of 21:25, 7 September 2022
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	*[[Electrolyte abnormality]]		*[[Electrolyte abnormality]]
	*[[Acute hepatic failure]]		*[[Acute hepatic failure]]

	~~{{Hepatomegaly DDX}}~~

	===[[Jaundice]]===		===[[Jaundice]]===
	*[[~~Hepatitis~~]]		*[[Hepatic dysfunction]]
			*[[Biliary disease]] (e.g. [[Choledocholithiasis\|CBD obstruction]])
	*[[hemolytic anemia\|Hemolysis]]		*[[hemolytic anemia\|Hemolysis]]
	*[[Biliary disease]] (e.g. [[Choledocholithiasis\|CBD obstruction]])
	*[[Pregnancy]]		*[[Pregnancy]]
	*Congenital diseases (e.g. [[inborn errors of metabolism]]; (more likely to present in early childhood)		*Congenital diseases (e.g. [[inborn errors of metabolism]]; (more likely to present in early childhood)

Rossdonaldson1: /* Encephalopathy (altered mental status) */

2022-09-07T21:24:16Z

Encephalopathy (altered mental status)

← Older revision		Revision as of 21:24, 7 September 2022
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	*[[Electrolyte abnormality]]		*[[Electrolyte abnormality]]
	*[[Acute hepatic failure]]		*[[Acute hepatic failure]]

			{{Hepatomegaly DDX}}

	===[[Jaundice]]===		===[[Jaundice]]===

Rossdonaldson1 at 21:20, 7 September 2022

2022-09-07T21:20:23Z

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 {{Acute hepatitis causes}}
+{{Drug or Toxin Related Liver Disease}}
 ===Other Rare Causes of Acute Liver Failure===