View source for Scopolamine

==Administration==
*Type: [[Anticholinergics]], [[Cycloplegic]]
*Dosage Forms:
*Routes of Administration: scopolamine- transdermal. Scopolamine hydrobromide- IV, oral, Ophthalmic
*Common Trade Names:

==Adult Dosing==
*0.32-0.1mg IV/IM/SubQ
*0.4-0.8mg PO
*1-2 drops (0.25% ophthalmic solution) up to 4 times daily
*1 transdermal patch q72h (each 1.5mg patch delivers 1mg scopolamine over 72h)

==Pediatric Dosing==
*Sedation:
**6mo-3y: 0.1-0.15 mg IM/IV/subQ
**3-6y: 0.2-0.3 mg IM/IV/subQ
*Vomiting: 6 mcg/kg subQ
*Transdermal patch not FDA-approved for children

==Special Populations==
*[[Drug pregnancy categories|Pregnancy Rating]]: C
*Lactation risk: infant risk is minimal
*Renal dosing: contraindicated in renal impairment
*Hepatic dosing: contraindicated in hepatic impairment

==Contraindications==
*Allergy to class/drug
*Glaucoma
*Chronic lung disease (repeated doses)
*Prostatic hypertrophy
*Pyloric obstruction

==Adverse Reactions==
===Serious===
*Tachyarrhythmia
*Hallucinations, confusion
*Glaucoma
*Systemic absorption of ophthalmic formulation
===Common===
*Dry skin, diminished sweating
*Xerostomia
*Amnesia, somnolence
*Mydriasis, blurred vision
*Local irritation

==Pharmacology==
*Half-life: 9.5h (transdermal)
*Metabolism: 
*Excretion: 

==Mechanism of Action==
*Belladonna alkaloid with anticholinergic (predominantly antimuscarinic) properties

==Comments==



==Indications by Condition==
''The following table is automatically generated from disease/condition pages across WikEM.''

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 |?Has Dose=Dose
 |?Has Context=Context
 |?Has Route=Route
 |?Has Population=Population
 |format=broadtable
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==See Also==
*[[Anticholinergic toxicity]]

==References==
<references/>

[[Category:Pharmacology]]